EP 41: Covid 19 vaccine passports and gun laws

EP 41: Covid 19 vaccine passports and gun laws

Are Covid Vaccine passports the next push?

The little paper card you got with your Covid shot could be your passport back to normal life

“Whether it’s school, entertainment venues, or travel, there’s going to be an expectation that to resume these activities you have to be retested and enter quarantine or produce proof of immunization,” Dr. John Brownstein, an epidemiologist at Boston Children’s Hospital, told ABC News.

In other words, people trying to do the kind of things they did before the pandemic – like a fly on a plane or see a movie in a cinema – may soon be required to prove they’ve been vaccinated. 

One of the executive orders President Biden signed in January, called for government officials to “assess the feasibility of linking Covid-19 vaccination to International Certificates of Vaccination or Prophylaxis (ICVP) and producing electronic versions of ICVPs” – all your Covid-related health records, together in one digital document.

Airlines are working on something similar. The International Air Transport Association has developed the “IATA Travel Pass,” a smartphone app that compiles a traveler’s vaccination status and Covid test results into easily scanned QR codes.

“A vaccination card is a tool that people can use to declare that they have some level of protection against COVID,” Dr. Brownstein said. “Being able to assess immunity to Covid is a critical part of trying to resume our daily lives.”

In addition to I.A.T.A., IBM has been developing its own Digital Health Pass that would enable individuals to present proof of vaccination or a negative test to gain access to a public location, such as a sports stadium, airplane, university, or workplace. The pass, built on IBM’s blockchain technology, can utilize multiple data types, including temperature checks, virus exposure notifications, test results, and vaccine status.

The World Economic Forum and the Commons Project Foundation, a Swiss nonprofit group, have been testing a digital health passport called CommonPass, which would allow travelers to access testing or vaccination information. The pass would generate a QR code that could be shown to authorities.

Counterpoint

There already is a vaccine passport. It’s easy to get. And its source is impeccable. As of June 15th, 2007. 

Nicknamed “the yellow card,” it’s a small, passport-sized yellow pamphlet officially titled “International Certificate of Vaccination as approved by the World Health Organization.”

The yellow card is an official medical record, recognized worldwide, of the diseases you’ve been immunized against.

The yellow card started due to yellow fever, the WHO reported that “32 African countries are now considered at risk of yellow fever, with a total population of 610 million people, among which more than 219 million live in urban settings. Some countries won’t let you in without medical proof that you’ve had the right vaccines or gotten them far enough in advance of your trip for them to be fully protected when you arrive. 

Vaccine passports being sold on darknet

Fake vaccination certificates are also being sold by anonymous traders for as little as $150 using the hard-to-trace cryptocurrency Bitcoin as the payment method.

Researchers at cyber-security company Check Point have monitored hacking forums and other marketplaces since January, when vaccine adverts first appeared.

They say the number of adverts they have seen has tripled to more than 1,200.

Sellers of vaccines appear to be from the US, UK, Spain, Germany, France and Russia. 

https://www.independent.co.uk/news/world/americas/vaccine-passport-us-covid-who-b1821421.html

https://www.who.int/ihr/ports_airports/icvp/en/

https://www.nytimes.com/2021/02/04/travel/coronavirus-vaccine-passports.html

https://www.bbc.com/news/technology-56489574

Boulder, CA shooting

Investigators on Tuesday were trying to determine what motivated a 21-year-old man, charged in the shooting at a Boulder, Colo., grocery store, to take the lives of 10 people, in the second mass shooting in the United States in less than a week.

The gunman was armed with both a military-style semiautomatic rifle and a pistol when he walked into the King Soopers store on Monday and opened fire, officials said. They identified the suspect who was arrested at the scene as Ahmad Al Aliwi Alissa, who lived in Arvada, a nearby suburb; he was charged on Tuesday with 10 counts of first-degree murder, which in Colorado carries a penalty of life imprisonment without parole.

Barack Obama has blasted “cowardly” Republicans for blocking gun control laws limiting “weapons of war” in the wake of the Boulder mass shooting.

Atlanta, Georgia Shooting

On March 16, 2021, a series of mass shootings occurred at three spas or massage parlors in the metropolitan area of Atlanta, Georgia, United States. Eight people were killed, six of whom were Asian women, and one other person was wounded. A suspect, 21-year-old Robert Aaron Long, was taken into custody later that day.

According to police, Long said he was motivated by a sexual addiction that was at odds with his religious beliefs. He had previously spent time in an evangelical treatment clinic for sex addiction. After the shootings, Long was charged with four counts of murder in Atlanta, and four counts of murder, and one count of aggravated assault in Cherokee County.

Although Long has not been charged with a hate crime as part of the ongoing investigation, some commentators have characterized the shootings as a hate crime, noting the backdrop of rising anti-Asian sentiment in the United States during the COVID-19 pandemic.

Biden Administration Urges Supreme Court To Let Cops Enter Homes And Seize Guns Without A Warrant

This term, the Supreme Court has an opportunity to apply the original meaning of the right “to be secure” to clarify the scope of the community caretaking exception to the Fourth Amendment’s warrant requirement.

In Caniglia v. Strom, Edward and Kim Caniglia, husband and wife, had a disagreement in their Rhode Island home. Mr. Caniglia retrieved his unloaded handgun and asked “why don’t you just shoot me and get me out of my misery?” Mrs. Caniglia left and spent the night in a motel. The next morning, Mrs. Caniglia called the police to escort her home. Police believed Mr. Caniglia could be a threat to himself so they brought him in for a psychiatric evaluation, which he agreed to only after police promised not to take his handguns. After Mr. Caniglia was admitted to the hospital—and despite their promise—the officers entered the home and seized the guns, which they returned when Mr. Caniglia sued.

The officers invoked the “community caretaking” exception to the warrant requirement to justify their warrantless entry of Mr. Caniglia’s home.

That exception stems from Cady v. Dombrowski, a case involving a crashed car that police had towed to a private garage and later searched, finding a revolver. The warrantless vehicle search was upheld because (at least according to the majority) police had control of the car and a search was necessary to remove potential safety threats.

The ultimate question, in this case, is therefore not whether the respondent officers’ actions fit within some narrow warrant exception

https://www.forbes.com/sites/nicksibilla/2021/03/23/biden-administration-urges-supreme-court-to-let-cops-enter-homes-and-seize-guns-without-a-warrant/?sh=69128bbd2829

https://ballotpedia.org/Caniglia_v._Strom

CON EP 40: Stimulus Checks & Why Covid Vaccines Are Gene Therapies

CON EP 40: Stimulus Checks & Why Covid Vaccines Are Gene Therapies

Stimulus Checks

About 85% of people will receive a $1400 stimulus check. It’s the third stimulus check since COVID 19 started. If you’ve filled your 2020 taxes the check will be based on those, if not it will go off 2019 taxes. 

Qualifying group What the law says
Individuals An AGI of less than $80,000 to qualify for any payment amount
Head of household An AGI of less than $120,000 to qualify for any payment amount
Couple filing jointly An AGI of less than $160,000 to qualify for any payment amount
Dependents of all ages $1,400 apiece, no cap — but only if guardians make under the above limits
Families with mixed US citizenship Provided they meet other qualifications
US citizens living abroad Yes, same as the first two checks
Citizens of US territories Yes, same as the first two checks, with payments handled by each territory
SSDI and other tax nonfilers Yes, but may require an extra step to claim (more below)
Incarcerated people Yes, included this time
People who owe child support Checks can be garnished to cover past due payments (more below)
Disqualified groups Not covered by law
Non-US citizens “Resident aliens” aren’t included
Noncitizens who pay taxes Depends on “mixed-status” rules (more below)

 

If you’ve had a child in 2021 they won’t be counted towards the stimulus, as of now. 

https://www.cnet.com/personal-finance/new-stimulus-check-everyone-who-qualifies-for-a-new-payment/

What is hidden in the Covid relief bill for Bill?

Bill and Malinda Gates foundation is reported to receive 3.5 billion.

The covid relief bill was 1.9 trillion. 

  • Expanded unemployment benefits until Sept. 6 at $300/week
    • About 57 million people filed for unemployment = 17 billion dollars
  • If 150 million people get 1400 then that equals 210 billion dollars
  • 350 billion to state and local governments
  • 130 billion into schools K-12
  • 40 billion for colleges and universities
  • 28.6 billion to businesses
  • 7.25 billion for the paycheck protection program
  • 50 billion to expand covid testing
  • 15 billion for covid distribution
  • 1 billion to boos vaccine confidence
  • 10 billion for medical supplies and devices. 
  • Increased tax breaks for families with children 
  • 30 billion for low-income households for rent
  • 10 billion for homeowners struggling with mortgages
  • Student loan forgiveness

Adds up to about 1 trillion

https://www.yahoo.com/entertainment/heres-everything-know-covid-19-191807754.html

Vaccine

The vaccine is technically a type of gene therapy. 

The definition of a vaccine ”is a substance used to stimulate the production of antibodies and provide immunity against one or several diseases, prepared from the causative agent of a disease, its products, or a synthetic substitute, treated to act as an antigen without inducing the disease.” 

https://www.dictionary.com/browse/vaccine?s=t

The definition of gene therapy is “the application of genetic engineering to the transplantation of genes into human cells in order to cure a disease caused by a genetic defect, as a missing enzyme.”

https://www.dictionary.com/browse/gene-therapy?s=t

How is the vaccine different?

Instead of antigen payloads, the vaccine carries copies of the recipe for making the antigen, in the form of RNA, a molecule that stores information.

RNA is a string of chemical units representing, similarly to letters of the alphabet, the genetic code that all living cells use as instructions for producing their component proteins.

The newly licensed COVID-19 vaccines contain myriad identical RNA strands all coding for a critical section of the coronavirus’s spike protein. This protein is easy for the immune system to attack because it sits on the virus’s outer surface. It’s also indispensable to the virus, as it’s absolutely required for entry into our cells; so the virus doesn’t have the option of altering its spike protein, via mutation, to escape immune detection.

The vaccine’s RNA strands are hidden inside of nanoscale fat globules, which keeps our immune systems from flipping out.

The primary target for an RNA vaccine, as for traditional vaccines, is dendritic cells. Which absorb the nano fat globules.

Once inside, the RNA strands make their way to protein-producing power tools called ribosomes.

The ribosomes decipher the strands’ coded instructions and churn out new SARS-CoV-2 spike-protein bits

This triggers an effect similar to traditional vaccines, in which dendritic cells displaying their antigenic trophies on their surfaces race to the lymph nodes to tip off the immune cells hanging out there.

CON EP 39: Our Journey Running the David Goggins 4x4x48 Challenge

CON EP 39: Our Journey Running the David Goggins 4x4x48 Challenge

In this episode, we will be talking about our 4x4x48 challenge experience. Running a marathon seems extreme but we managed to run 48 miles in two days, here is our experience.

Questions we address

  • Why did you do the 4x4x48
  • First impressions of the challenge
  • How much running did you do before the challenge? 
  • Did you think the challenge is hard – doable?
  • Training before the challenge?
  • Diet before the challenge?
  • Diet plan for the challenge?
  • How were your eating habits?
  • Favorite snacks? meals? drinks? 
  • What was your favorite pick me up?
  • Did you have a ritual before each run?
  • Did you massage regularly?
  • Did you do any breathing exercises? Ice bath? 
  • The hardest part about starting each new 4-mile segment?
  • The hardest point of the whole challenge?
  • When did you feel the pain start to creep in?
  • Favorite part of the challenge?
  • Would you recommend this challenge to anyone or is it more for extreme fitness athletes?
  • Source of motivation during the challenge?
CON EP 38: Does Governor Cuomo Deserve a Emmy

CON EP 38: Does Governor Cuomo Deserve a Emmy

In this episode, we will be talking about the Cuomo controversy and a few other public figures who lied to congress, and some covid-19 updates. Late-night 2 am Recording from Austin, TX.

Cuomo’s Award for Masterful Covid Briefings

Governor Andrew M. Cuomo of New York will receive this year’s International Emmy Founders Award, in recognition of his leadership during the Covid-19 pandemic and his masterful use of television to inform and calm people around the world.

https://www.iemmys.tv/new-york-governor-andrew-m-cuomo-to-receive-2020-international-emmy-founders-award/

“The Governor’s 111 daily briefings worked so well because he effectively created television shows, with characters, plot lines, and stories of success and failure,” the academy’s president and CEO, Bruce Paisner, explained in a statement announcing the decision. “People around the world tuned in to find out what was going on, and New York tough became a symbol of the determination to fight back.”

https://www.npr.org/sections/coronavirus-live-updates/2020/11/21/937445923/andrew-cuomo-to-receive-international-emmy-for-masterful-covid-19-briefings

Democratic New York Gov. Andrew Cuomo is at the center of an escalating controversy over deaths in nursing homes, how they were counted and how they handled requests for that data.

State Attorney General Letitia James issued a report in January finding that the New York State Department of Health undercounted Covid-19 deaths among residents of nursing homes by approximately 50%, essentially by leaving out deaths of residents who had been transferred to hospitals.

https://www.cnn.com/2021/02/15/politics/andrew-cuomo-covid-19-controversy-explained/index.html

Public figures who lied to congress

  1. Nixon and Watergate
    1. The Watergate scandal was a scandal during and after the 1972 Presidential Election.
    2. United States President and Republican Richard Nixon were running for election against Democrat George McGovern. Frank Wills, a security guard, discovered clues that former FBI and CIA agents broke into the offices of the Democratic Party and George McGovern months before the election. These people listened to phone lines and secret papers were stolen.
    3. When these men were found, it turned out that Nixon was involved and he had helped them cover it all up and might have even hired the men.
  2. Harvey Matusow
    1. Matusow, an ex-Communist who had become an FBI informant, was convicted of lying to Congress in the 1950s after revealing in his book “False Lies,” that in testimony to lawmakers, he had falsely named 200 people as Communists or Communist sympathizers just a few years earlier. 
  3. Caspar Weinberger
    1. Weinberger, a former Defense secretary, was indicted on felony charges in 1992 for lying to Congress about his role in the Iran-Contra scandal during the Reagan administration, in which officials sold arms to the Iranian government to support militant rebels in Nicaragua.

https://www.nbcnews.com/politics/congress/5-people-who-lied-congress-what-happened-them-n941936

U.S. COVID-19 Death Toll Reaches 500,000

January 8th: 260k new case 7-day average 

February 22nd: 67k new cases 7-day average 

That’s 74.3% reduction in corona virus cases in the past month, how come no one is covering that?

“We want firm recommendations from the CDC, which I believe will be coming soon” for interactions with “fully vaccinated people,” Dr. Anthony Fauci told CNN on Tuesday morning. The director of the National Institute of Allergy and Infectious Diseases said he expects those guidelines to include less-stringent recommendations regarding quarantines for those who have been fully vaccinated.

So far, the available Covid-19 vaccines have not been judged primarily on their ability to prevent transmission – though this is now being evaluated as a secondary endpoint for many of them. Instead, their efficacy was assessed by whether they could prevent symptoms from developing

So far, 19.44 million people in the United States have been fully vaccinated for Covid, meaning they’ve received both doses, according to Our World in Data.

Essential elements for K-12 schools to reopen

Five key mitigation strategies are essential to the safe delivery of in-person instruction and help to mitigate COVID-19 transmission in schools:

  • Universal and correct use of masks
  • Physical distancing
  • Handwashing and respiratory etiquette
  • Cleaning and maintaining healthy facilities
  • Contact tracing in combination with isolation and quarantine, in collaboration with the health department

 

We should not have an oppressive state telling us what to do.

The 6-foot social-distancing rule is based on nearly 80-year-old science.

In the early 1940s, scientists finally got their first glimpses of people’s sneezes hurtling through the air in real-time, at a capture rate of 30,000 frames a second, confirming that indeed, most of the stuff we throw into the air when we sneeze, cough, or yell tends to settle down to the ground within about a wingspan or so (say, 3 to 6 feet).

“The dogma was born,” professor Lidia Morawska, a leading aerosol scientist in Australia, said of the 80-year-old 6-foot rule. “Like any dogma, it’s extremely difficult to change people’s minds and change the dogmas.” 

 

CON EP 37: 4x4x48, Refined Grains and Negative Side Effects of Soybean Oils

CON EP 37: 4x4x48, Refined Grains and Negative Side Effects of Soybean Oils

In this episode, we will be talking about our 4x4x48 journey, the David Goggins-inspired run. We’ll also share some research we found regarding refined grains and the negative effects of soybean oil.

What are refined grains?

“Refined grain” is the term used to refer to grains that are not whole, because they are missing one or more of their three key parts (bran, germ, or endosperm). White flour and white rice are refined grains.

Whole grains are nutrient-packed with fiber, B vitamins, antioxidants, vitamin E, and protein. With all these wonderful compounds, whole grains are nutrient superior to refined grains.

  • Fiber is the part of the plant we don’t digest and help us feel full for longer periods of time making it useful for weight control. 
  • Vitamin E is a powerful antioxidant that helps us combat disease and stay healthy. 
  • B vitamins help us feel energetic. Those are definitely great reasons to eat more whole grains: oats, quinoa, barley, and brown rice among many others.

Refined Grains and negative health outcomes

Associations of cereal grains intake with cardiovascular disease and mortality across 21 countries

https://www.bmj.com/content/372/bmj.m4948

  • Data on people 148 858 aged 35 to 70 years at baseline were collected from 21 countries. – 137 130 participants after exclusion
  • The highest category of intake of refined grains (≥350 g/day or about 7 servings/day) was associated with a higher risk of total mortality and major cardiovascular disease events.
  • We did not find significant associations of consumption of whole grains or white rice with total mortality and cardiovascular outcomes.

Relationship between bread and obesity

https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/relationship-bread-and-obesity/96FE4C069F8C4E2D04AE8F44094D787A

  • A systematic review of white bread effect on fat and weight gain
  • Bread consumption, which has been part of the traditional Mediterranean diet, has continued to decline in Spain and in the rest of the world because the opinion of the general public is that bread fattens. The present study was conducted to assess whether or not eating patterns that include bread are associated with obesity and excess abdominal adiposity
  • Consumption of whole-grain bread was more beneficial than refined bread, especially in relation to abdominal fat.
    • (a) Whole-grain bread: does not influence weight gain. (b) White bread: possible relationship with excess abdominal fat.
  • 14 studies
    • 5 found refined wheat to increase fat
    • 5 studies showed the benefit of whole grain over white
    • 4 studies show no relationship between food groups that included bread

Breakfast Cereal Consumption and Obesity Risk amongst the Mid-Age Cohort of the Australian Longitudinal Study on Women’s Health

https://www.mdpi.com/2227-9032/5/3/49

  • Longitudinal study
  • Any breakfast cereal intake was not associated with incident obesity
  • Oat-based, muesli, and bran-based cereal intakes were associated with a significant reduction in obesity risk. 
  • muesli on its own, or as part of oat-based cereals, and All-Bran, were associated with a reduction in obesity.

Glycemic load, glycemic index, bread and incidence of overweight/obesity in a Mediterranean cohort: the SUN project

https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-14-1091

  • Followed-up 9 267 Spanish university graduates for a mean period of 5 years.
  • White bread and whole-grain bread were not associated with higher weight gain. No association between glycemic index, glycemic load, and weight change was found.
    • White bread consumption was directly associated with a higher risk of becoming overweight/obese.
    • Consumption of white bread (≥2 portions/day) showed a significant direct association with the risk of becoming overweight/obese.

The Negative effects of Soybean Oil 

Soybean oil is used in fast food frying and packaged foods and fed to livestock. Its use in the U.S. increased 1,000 times throughout the 20th century, the researchers said.

The dogma is that saturated fat is bad and unsaturated fat is good. Soybean oil is polyunsaturated fat, but the idea that it’s good for you is just not proven

A diet high in soybean oil causes more obesity and diabetes than a diet high in fructose, a sugar commonly found in soda and processed foods, according to a just-published paper by scientists at the University of California, Riverside.

This study was done by scientists who fed male mice a series of four diets that contained 40 percent fat, similar to what Americans currently consume. The diet mimics what the average American consumes daily.

Four different diets:

  • Coconut oil – primarily saturated fat
  • Half coconut oil and soybean oil-primarily polyunsaturated fats and is the main ingredient in vegetable oil. 
  • The other two had added Fructose to the above, comparable to the amount consumed by Americans. 

Compared to mice on the high coconut oil diet, mice on the high soybean oil diet showed increased weight gain, larger fat deposits, a fatty liver with signs of injury, diabetes, and insulin resistance, all of which are part of the Metabolic Syndrome. Fructose in the diet had less severe metabolic effects than soybean oil although it did cause more negative effects in the kidney and a marked increase in prolapsed rectums, a symptom of inflammatory bowel disease (IBD), which like obesity is on the rise.

Results

The mice on the soybean oil-enriched diet gained almost 25 percent more weight than the mice on the coconut oil diet and 9 percent more weight than those on the fructose-enriched diet. And the mice on the fructose-enriched diet gained 12 percent more weight than those on a coconut oil rich diet.

The major surprise is soybean oil causes more obesity and diabetes than fructose.

https://ucrtoday.ucr.edu/30416

How Are Industrial Seed Oils Made?

The general process used to create industrial seed oils is anything but natural. The oils extracted from soybeans, corn, cottonseed, safflower seeds, and rapeseeds must be refined, bleached, and deodorized before they are suitable for human consumption.

  1. First, seeds are gathered from the soy, corn, cotton, safflower, and rapeseed plants.
  2. Next, the seeds are heated to extremely high temperatures; this causes the unsaturated fatty acids in the seeds to oxidize, creating byproducts that are harmful to human and animal health.
  3. The seeds are then processed with a petroleum-based solvent, such as hexane, to maximize the amount of oil extracted from them.
  4. Next, industrial seed oil manufacturers use chemicals to deodorize the oils, which have a very off-putting smell once extracted. The deodorization process produces trans fats, which are well known to be quite harmful to human health.
  5. Finally, more chemicals are added to improve the color of the industrial seed oils.

From Toxic Waste to “Heart Healthy”: The History of Seed Oils

The surprising story of how seed oils were classified as “heart-healthy” involves a scandalous combination of donations to medical organizations.

In the late 1940s, a small group of cardiologists who were members of the still somewhat new American Heart Association received a $1.5 million donation from Procter & Gamble; thanks to this generous infusion of cash from the makers of Crisco, the AHA now had sufficient funding to grow its national profile as a physician’s organization dedicated to heart health. It also was quick to endorse industrial seed oils, more kindly referred to by now as “vegetable oils,” as a healthier alternative to traditional animal fats.

Around the same time, a physiologist and researcher named Ancel Keys introduced his diet–lipid hypothesis, in which he presented data that seemed to suggest a link between saturated fat and cholesterol intake and heart disease. Citing animal fats as “unhealthy,” Keys instead recommended the consumption of polyunsaturated fatty acids (PUFAs), which preliminary research had associated with reductions in cholesterol and the risk of heart disease. Keys’ conclusions were in line with the industrial seed oil industry’s motives—to get people to eat more seed oils! Soon, ads for “heart-healthy” margarine (a solid form of vegetable oil) and other seed oils became commonplace, and healthy, traditional fats were all but forgotten.

https://chriskresser.com/how-industrial-seed-oils-are-making-us-sick/

What does P&G own?

https://en.wikipedia.org/wiki/List_of_Procter_%26_Gamble_brands

Soybean Oil Induces Genetic Changes in Brain Region Controlling Metabolism

The study, “Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice,” was published in the journal Endocrinology.

The findings indicate that, besides its effects on obesity, this oil affects the brain control of insulin signaling and inflammation, while also having an impact on neurological pathways important in depression and Alzheimer’s disease.

The hypothalamus harbors brain cells that play pivotal roles in the control of body fat — adipose tissue — by regulating the balance between caloric intake and energy expenditure. Hypothalamic cells release small molecules, such as the hormone oxytocin, whose role in regulating food intake and energy spending has increasingly been recognized.

The researchers fed mice with three different diets high in fat — soybean oil, soybean oil modified to be low in linoleic acid, and coconut oil (control). The mice were fed twice weekly for up to 24 weeks.

The results showed that both soybean oil diets induced significant changes in over 100 hypothalamic genes compared with the coconut oil diet. The coconut oil diet used that oil as a regular oil without linoleic acid or stigmasterol — a cholesterol-like molecule that also is the main component of soybean oil — as well as a coconut oil supplemented with stigmasterol.

The genes with altered activity were involved not only in processes such as inflammation and insulin signaling, but also in signaling pathways important in anxiety, depression, and Alzheimer’s.

One such gene was the Oxt gene, which generates oxytocin. Levels of this hormone, which also has been associated with obesity, were reduced in the hypothalamus and appeared to lead to an increase in glucose sensitivity — an indicator of diabetes.

The Oxt gene is associated with neurological, metabolic, and inflammatory diseases that showed increased activity in both soybean oil diets. 

In additional experiments, the scientists confirmed that the impact of soybean oil on the hypothalamus was not linked with linoleic acid nor stigmasterol.

https://geneticobesitynews.com/2020/01/30/soybean-oil-induces-genetic-changes-brain-region-controlling-metabolism-linked-obesity-mouse-study/#:~:text=Studies%20in%20mice%2C%20however%2C%20have,less%20obesity%20and%20insulin%20resistance.

https://academic.oup.com/endo/article/161/2/bqz044/5698148

CON EP 36: Covid-19 Case Perspective & Diabetic Foot Ulcers

CON EP 36: Covid-19 Case Perspective & Diabetic Foot Ulcers

In this episode, we will be talking about Covid Case Perspectives, diabetic foot ulcer drug & the race to Mars between the USA, China, and United Arab Emirates (UAE). 

Covid Case Perspective

We took a look at the recent covid cases from Albuquerque, New Mexico. They had 13 new covid deaths reported. 

What do we see?

  • 1 death of a 20-year-old with underlying conditions.
  • 1 death of a 50-year-old with underlying conditions and a resident of a nursing home.
  • 1 death of a 60-year-old with underlying conditions.
  • 4 deaths of 70-year-olds with underlying conditions.
  • 4 deaths of 80-year-olds with underlying conditions.
  • 2 deaths of 90-year-old underlying conditions and a resident of a nursing home

https://www.kob.com/albuquerque-news/new-mexico-reports-13-new-deaths-349-additional-covid-19-cases/6005206/

Covid 19 case estimates

We haven’t tested everyone in the US so we cannot get the exact infection rate or a number of cases so there are different estimates. One, in particular, we found interesting because it shows the case rate to be much higher than reported. A research team from the Columbia institute built a mathematical model that gives a much more intuitive,  and scary, picture of how much virus is circulating in our country. 

It is reported that 8% of the US has been infected, however, the research team’s mathematical model estimates that about 36% of the US population has had covid 19. 

https://www.npr.org/sections/health-shots/2021/02/06/964527835/why-the-pandemic-is-10-times-worse-than-you-think

Feb 7th – 41 million vaccine doses administered. 

Diabetic foot ulcers

Of the most common and most severe complications of diabetes is diabetic foot ulcer which affects approximately 15% – 20% of people with diabetes and frequently leads to amputation of the lower limb.

Diabetic foot ulcer occurs when an ulcer or a wound develops in an area in the lower legs or feet which do not heal or is difficult to treat leading to the exposure of the underlying tissue and become susceptible to infections.

One of the main contributing factors to developing diabetic foot ulcers is peripheral neuropathy (nerve damage) which arises due to an increase in blood sugar level.  Due to nerve damage and loss of sensations and the ability to feel pain, foot damage, even from such simple things as pressure from shoes or a small cut, go unnoticed and unprotected resulting in worsening skin loss, blisters, and a possibility of serious infection than may progress in a matter of days.

Treatment of Diabetic foot ulcers

It has been shown that diabetic patients have decreased growth factor concentrations in their tissues, particularly epidermal growth factors. Growth factor shortage impairs wound healing, which leads to chronic nonhealing wounds and sometimes eventual amputation. An ischemic diabetic foot ulcer is the most difficult to treat and confers the highest amputation risk. 

For Diabetic Foot Ulcer, Heberprot-P is a drug developed by the Center for Genetic Engineering and Biotechnology (CIGB) in 2007 in Cuba.

 About 160,000 diabetic foot ulcer patients have been treated with Heberprot-P with success reducing the risk of amputation by 77%.

Recent reviews suggest that the total costs of treating a diabetic foot ulcer range from $10,000 to nearly $60,000.

The treatment of diabetic ulcers is complex. The fundamentals of good clinical care include adequate off-loading, frequent debridement, moist wound care, treatment of infection, and revascularization of ischemic limbs.

The United States Embargo against Cuba prevents American businesses and businesses with commercial activities in the United States, from conducting trade with Cuban interests.

With technological advancement, other series of therapies for DFUs have been implemented, such as the development of skin substitutes, negative pressure wound therapy, hyperbaric oxygen, the creation of new wound dressings that include growth factors, and the use of tissues from bioengineering.

This is a link for foot care for wounds at home: https://my.clevelandclinic.org/health/diseases/17169-leg-and-foot-ulcers/management-and-treatment

Current Therapeutic Strategies in Diabetic Foot Ulcers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915664/

https://pubmed.ncbi.nlm.nih.gov/23396236/#:~:text=Heberprot%2DP%20is%20an%20innovative,and%20reduces%20diabetes%2Drelated%20amputations.

https://care.diabetesjournals.org/content/26/6/1879#:~:text=A%20total%20of%20%E2%88%BC2.5,foot%20or%20limb%20(3).

https://www.cubaheal.com/2018/12/11/treatment-for-diabetic-foot-ulcer-heberprot-p/

EGF infiltration increased and accelerated healing in poor-prognosis wounds toward a rapid and sustained response. More than 80% granulation was obtained globally with HeberprotP, in comparison with less than 60% with standard care alone. Of patients treated with Heberprot-P at 75 μg, three times per week until complete granulation (or during 8 weeks) in association with standard care, 77% healed; while only 56% healed with placebo injections and standard care.

https://mediccreview.org/wp-content/uploads/2018/04/mr_287.pdf

Race to Mars

The first Arab space mission, the UAE’s “Hope” probe, is expected to reach Mars’ orbit on 9 February, making it the first of three spacecraft to arrive at the Red Planet this month.

The United Arab Emirates, China, and the United States all launched projects to Mars last July, taking advantage of a period when the Earth and Mars are nearest.

After blasting off from Japan last July, the Hope mission now faces its “most critical and complex” maneuver, according to Emirati officials, with a 50-50 chance of successfully entering a Mars orbit.

The spacecraft must slow significantly to be captured by Martian gravity, rotating and firing all six of its Delta-V thrusters for 27 minutes to reduce its cruising speed of 121,000 kilometers (about 75,000 miles) per hour to about 18,000 km/h (11,200 mph). 

The process, which will consume half of its fuel, will begin on Tuesday, Feb. 9, at 15:30 GMT (15:30 UTC) and it will take 11 minutes for a signal on its progress to reach ground control.

NASA’s Perseverance, which is set to touch down on the Red Planet on February 18, will become the fifth rover to complete the voyage since 1997 – and all so far have been American.

It is on an astrobiology mission to look for signs of ancient microbial life and will attempt to fly a 1.8 kilogram helicopter-drone on another world for the first time. 

Perseverance, capable of autonomously navigating 200 meters (650 feet) per day, will collect rock samples that could provide invaluable clues about whether there was ever past life on Mars.

About the size of a small SUV, it weighs a metric tonne, has 19 cameras and two microphones – which scientists hope will be the first to record sound on Mars.

The mission is set to last at least two years.

https://www.sciencealert.com/the-uae-s-hope-probe-expected-to-win-the-2020-race-to-mars